50 Club

  • 65. Identifying the Roles of Amino Acids, Alcohols and 1,2-Diamines as Mediators in Coupling of Haloarenes to Arenes

    Coupling of haloarenes to arenes has been facilitated by a diverse range of organic additives in the presence of KOtBu or NaOtBu since the first report in 2008. Very recently, we showed that the reactivity of some of these additives (e.g. compounds 6 and 7 in Figure 1) could be explained by the formation of […]

    Shengze Zhou, S.-z.; Doni, E.; Anderson, G. M.; Kane, R. G.; MacDougall, S. W.; Ironmonger, V.; Tuttle, T.; Murphy, J. A.

    J. Am. Chem. Soc. 2014 136 17818

  • 62. Discovery of Catalytic Phages by Biocatalytic Self-Assembly

    Discovery of new catalysts for demanding aqueous reactions is challenging. Here, we describe methodology for selection of catalytic phages by taking advantage of localized assembly of the product of the catalytic reaction that is screened for. A phage display library covering 109 unique dodecapeptide sequences is incubated with nonassembling precursors. Phages which are able to […]

    Maeda, Y.; Javid, N.; Duncan, K.; Birchall, L.; Gibson, K. F.; Cannon, D.; Kanetsuki, Y.; Knapp, C.; Tuttle, T.; Ulijn, R. V.; Matsui, H.

    J. Am. Chem. Soc. 2014 136 15893

  • 61. The Synthesis of Highly Active Iridium(I) Complexes and their Application in Catalytic Hydrogen Isotope Exchange

    Brown, J. A.; Cochrane, A. R.; Irvine, S.; Kerr, W. J.; Mondal, B.; Parkinson, J. A.; Paterson, L. C.; Reid, M.; Tuttle, T.; Andersson, S.; Nilsson, G. N.

    Adv. Synth. Catal. 2014 356 3551

  • 57. Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes

    Cochrane, A. R.; Idziak, C.; Kerr, W. J.; Mondal, B.; Paterson, L. C.;Tuttle, T.; Andersson, S.;Nilsson, G. N.

    Org. Biomol. Chem. 2014 12 3598