Group Leader

Dr. Tell Tuttle

Tell Tuttle's research is focused on the concept of "reducing molecular search spaces" - a term that was coined in the group. The group works closely with experimental colleagues to address practical problems in the areas of molecular structure (development of new materials), molecular recognition (drug design), molecular reactivity (new catalysts and new paradigms in organic reaction mechanisms) and molecular properties (development of organic photovoltaics). The understanding derived from the computational and theoretical methods employed in our research results in the generation of predictive models that are used to design molecular-based solutions to a range of problems from chemistry to biomedicine to nanotechnology to organic electronics.

Biography

2010 - date: Senior lecturer in physical organic chemistry at the University of Strathclyde, Glasgow, UK

2007 - 2010: Lecturer in Physical Organic Chemistry at the University of Strathclyde, Glasgow, UK

2004 - 2006: Post doc in the group of Prof. Walter Thiel at the Max Planck Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.

2002 - 2004: PhD thesis in theoretical chemistry, supervised by Prof. Dieter Cremer and Prof. Elfi Kraka at Göteborg University, Sweden.

2001: Honours year thesis in computational chemistry with Prof. Brian Yates at the University of Tasmania.

1998 - 2000: Undergraduate studies at the University of Tasmania. B.Sc with majors in physics and chemistry.

The Team

Current Group members

Graduate Students

Daniela Kroiss

Daniela obtained her B.Sc. in Food Science and Biotechnology and her M.Sc. in Medical Biotechnology from the University of Natural Resources and Life Sciences Vienna (Austria) after completing a final year project on human antibody receptors. She joined the Biochemistry Ph.D. program at CUNY in August 2015 and is currently working on a joint project between the City University of New York and the University of Strathclyde under the supervision of Prof. Rein Ulijn and Dr. Tell Tuttle. Her research focuses on designing stimuli responsive materials using biological fuel sources.

    Allan Young

    Allan’s work is focused on developing molecular clips containing super electron donors developed by the Murphy group, with the aim of replacing transition-metal catalysed cross-couplings. Allan uses Density Functional Theory to aid in the design of molecular clips, and hopes to use a meta-heuristic search optimiser to rank binding conformations of substrates following design of molecular clips.

      Marie-Pierre Dreanic

      My PhD is a collaborative programme between GSK and the University of Strathclyde. My project is about applying computational methods for a rational design of biocatalyst mainly using QM/MM methods. QM/MM calculations will allow me to gain further insight into enzyme's catalytic mechanisms and simulate the effect of mutations.

        Mark Allison

        Mark’s project will use a combination of computational theory and experimental work to assist in the development of novel organic super electron donors, with aim of transition metal free coupling reactions.

          Ines Moreira

          Inês is working towards a PhD in a collaborative project between Dr. Tell Tuttle and Prof. Rein Ulijn. Her project is on the self-assembly and molecular modelling of aromatic peptide amphiphiles. The objective is to both experimentally and computationally, evaluate these as emulsion stabilisers and to study their final supramolecular structures at the water/oil interface.

            Florimond Cumine

            The aim of Florimond’s project is to find organic electron donors, which can promote the coupling reactions between two aryl moieties without the requirement of any transition metal. His computational studies are mainly to check the energy barriers of the electron transfer reactions from an electron donor to an aryl halide (with Marcus theory) and of the coupling reaction cycle.

              Katie Emery

              Katie’s work is a combination of computational theory and synthetic studies in collaboration with Professor John Murphy. Katie applies density functional theory to gain further insight into her mechanistic studies, supporting her experimental work. Katie’s project uses an organic electron donor for the transition metal-free formation of -aryl carbonyl bonds.

                Gary Scott

                Gary is working with the field of molecular dynamics to discover how the self-assembly of peptide systems are driven. In a joint experimental and theoretical project, Gary uses the predictive tool of theoretical chemistry to hand pick interesting peptides that show self-assembling behaviour. The purpose of this is for implementation in the food industry where these self-assembly features enhance the structure of products or stabilise proteins.

                  Undergraduate Students

                  Laura Janssen

                  2017


                    Previous Group Members

                    Post Docs

                    Bhaskar Mondal

                    2010-2013

                      Jörg Sassmannshausen

                      2009-2010

                        Qinghua Ren

                        2008-2010

                          Graduate Students

                          Armelle Le Gall

                          2017

                            Greg Anderson

                            2016

                              Daniel Cannon

                              2016

                                Ivan Ramos-Sasselli

                                2016

                                  Marc Reid

                                  2015

                                    Nicola Caldwell

                                    2015

                                      Christopher Idziak

                                      2013

                                        Pim Frederix

                                        2013

                                          Undergraduate Project Students

                                          Christopher Faulkner

                                          2016-2017

                                            Iain Prentice

                                            2016-2017

                                              Samuel Stewart

                                              2016-2017

                                                Lauren Barrie

                                                2015-2016

                                                  Sarah Dyer

                                                  2015-2016

                                                    Luca Bartek

                                                    2015-2016

                                                      Victoria Lang

                                                      2015-2016

                                                        Emma Matthews

                                                        2014-2015

                                                          Louise Cranston

                                                          2013-2014

                                                            Kimberley Ross

                                                            2013-2014

                                                              Iain Cameron

                                                              2013-2014

                                                                Sarah Christmas

                                                                2012-2013

                                                                  Jessica Padden

                                                                  2012-2013

                                                                    Amy Romaniuk

                                                                    2012-2013

                                                                      Allan Young

                                                                      2012-2013

                                                                        Ivan Ramos-Sasselli

                                                                        2011-2012

                                                                          Deborah Cleary

                                                                          2011-2012

                                                                            Emily Bell

                                                                            2011-2012

                                                                              Kate Hannaby

                                                                              2010-2011

                                                                                Daniel Cannon

                                                                                2010-2011

                                                                                  Joe Cameron

                                                                                  2010-2011

                                                                                    Scott Flemming

                                                                                    2009-2010

                                                                                      Undergraduate Summer Students

                                                                                      Laura Janssen

                                                                                        Kirsty Anderson

                                                                                        2016

                                                                                          Pauline Verite

                                                                                          2016

                                                                                            Fabian Talbot

                                                                                            2015

                                                                                              Vincent Montigaud

                                                                                              2015

                                                                                                Jemma Machlachlan

                                                                                                2015

                                                                                                  Lisa Cowling

                                                                                                  2015

                                                                                                    Andy Roberts

                                                                                                    2012

                                                                                                      Ben Snow

                                                                                                      2012

                                                                                                        James Fox

                                                                                                        2009

                                                                                                          Tom Morrell

                                                                                                          2009

                                                                                                            Visiting Scholars

                                                                                                            Pardis Tabaee

                                                                                                              Frank Fischer

                                                                                                              Now PhD student in the Sauer Lab, HU Berlin